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REVIEW ARTICLE
Year : 2021  |  Volume : 7  |  Issue : 4  |  Page : 241-246

Protection of multiple ischemic organs by controlled reperfusion


1 Department of Neurology, Xuanwu Hospital, Capital Medical University, Beijing, China
2 Department of Neurology, Xuanwu Hospital; ChinaAmerica Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China
3 School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China
4 Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA
5 ChinaAmerica Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China; Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI, USA
6 ChinaAmerica Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing, China
7 Department of Neurology, Xuanwu Hospital; ChinaAmerica Institute of Neuroscience, Xuanwu Hospital, Capital Medical University; School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China

Correspondence Address:
Xunming Ji
Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing
China
Zhichen Yin
China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing
China
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bc.bc_59_21

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Reperfusion injury (RI) is a harmful complication that takes place during recanalization treatment of ischemic organs. Currently, there are no efficacious treatments for protecting the organs against RI. Therefore, it is necessary to discover new strategies to prevent RI. As a novel intervention technique, controlled reperfusion has promising effects on protecting multiple organs from RI, and it is done by adjusting physical parameters of blood flow or chemical compositions of the reperfusion liquid. In this brief review, the status of various controlled reperfusion methods is presented, as well as their application in the protection of ischemic organs.


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