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REVIEW ARTICLE
Year : 2022  |  Volume : 8  |  Issue : 1  |  Page : 1-5

Mini review: Prospective therapeutic targets of Alzheimer's disease


Department of Neurosurgery, Wayne State University School of Medicine, Detroit, Michigan, USA

Correspondence Address:
Yuchuan Ding
Department of Neurosurgery, Wayne State University School of Medicine, 540 E Canfield St., Detroit, Michigan 48201
USA
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/bc.bc_20_21

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Alzheimer's disease is a neurological condition that causes the disruption of neuronal connections in the human brain. It is progressive and targets about 10% of the United States population over the age of 65.3 to date, there is no cure to the disease. Physicians can treat symptoms but lack the ability to stop the progression of the disease. However, promising research has come to the surface in recent years. A collection of these therapeutic targets, which have yielded positive results in mice models, are presented in this article. They include targets such as meningeal lymphatics, mitochondrial homeostasis, genomic instability, calcium homeostasis, and cold-shock proteins such as RNA-binding motif protein 3 and reticulon-3, high-density lipoprotein, and antibodies.


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