Brain Circulation

REVIEW ARTICLE
Year
: 2021  |  Volume : 7  |  Issue : 3  |  Page : 167--177

Slit ventricle syndrome: Historical considerations, diagnosis, pathophysiology, and treatment review


Dimitrios Panagopoulos1, Ploutarchos Karydakis2, Marios Themistocleous1 
1 Department of Neurosurgery, Pediatric Hospital of Athens, “Agia Sophia,”, Athens, Greece
2 Department of Neurosurgery, 251 Greek Air Force Hospital, Athens, Greece

Correspondence Address:
Dimitrios Panagopoulos
Thivon and Papadiamantopoulou St, Goudi, 11527, Athens, Attica
Greece

After the introduction of shunt treatment for the management of childhood hydrocephalus, a wide variety of complications related to this treatment modality have been recognized. The entity of slit ventricle syndrome (alternatively, symptomatic ventricular coaptation) is one of them, is frequently encountered in the pediatric population and its symptom complex resembles that of shunt failure. We conducted research on PubMed®, MEDLINE®, and Web of Science®, using the keywords: “slit ventricles,” “slit ventricle syndrome,” “SVS” and “ventricular coaptation.” The aim of our review was to trace the advances made through the past decades, concerning our knowledge about the clinical characteristics, pathophysiology, and treatment options of this entity. The discrepancy among researchers about the offending etiology and the optimum treatment algorithm of this entity, as well as the necessity of an updated concept regarding shunt over drainage is analyzed. The multiple treatment modalities proposed and pathophysiologic mechanisms implicated for the treatment of slit ventricle syndrome illustrate the complexity of this entity. Consequently, the issue requires more detailed evaluation. In this review, we comment on all the main facets related to shunt over drainage and the resultant slit ventricle syndrome.


How to cite this article:
Panagopoulos D, Karydakis P, Themistocleous M. Slit ventricle syndrome: Historical considerations, diagnosis, pathophysiology, and treatment review.Brain Circ 2021;7:167-177


How to cite this URL:
Panagopoulos D, Karydakis P, Themistocleous M. Slit ventricle syndrome: Historical considerations, diagnosis, pathophysiology, and treatment review. Brain Circ [serial online] 2021 [cited 2022 Jan 27 ];7:167-177
Available from: http://www.braincirculation.org/article.asp?issn=2394-8108;year=2021;volume=7;issue=3;spage=167;epage=177;aulast=Panagopoulos;type=0