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Figure 1: Overview of Sirt1 mediated ischemic tolerance Left: IPC = Ischemic preconditioning, RPC = Resveratrol preconditioning, ALA = Alpha-lipoic acid, TSG = 2,3,5,4'-Tetrahydroxystilbene-2-O-ß-Dglucoside, NMN = Nicotinamide mononucleotide, NAMPT = Nicotinamide phosphoribosyltransferase Right: DNA repair, Mitochondrial function, Blood flow and neuroinfl ammation, Synaptic function, Antioxidation, NAD+ metabolism

Figure 1: <i>Overview of Sirt1 mediated ischemic tolerance
Left: IPC = Ischemic preconditioning, RPC = Resveratrol preconditioning, ALA = Alpha-lipoic acid, TSG = 2,3,5,4'-Tetrahydroxystilbene-2-O-ß-Dglucoside, NMN = Nicotinamide mononucleotide, NAMPT = Nicotinamide  phosphoribosyltransferase
Right: DNA repair, Mitochondrial function, Blood flow and neuroinfl ammation, Synaptic function, Antioxidation, NAD+ metabolism</i>